A PRACTICE-BASED TRIAL OF BLOOD PRESSURE CONTROL IN AFRICAN AMERICANS (TLC-CLINIC): STUDY PROTOCOL FOR A RANDOMIZED CONTROLLED TRIAL

A practice-based trial of blood pressure control in African Americans (TLC-Clinic): study protocol for a randomized controlled trial

Abstract Background Poorly controlled hypertension (HTN) remains one of the most significant public health problems in the United States, in terms of morbidity, mortality, and economic burden.Despite compelling evidence supporting the beneficial effects of therapeutic lifestyle changes (TLC) for blood pressure (BP) reduction, the effectiveness of t

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The MicroRNA Landscape of Acute Beta Cell Destruction in Type 1 Diabetic Recipients of Intraportal Islet Grafts

Ongoing beta cell death in type 1 diabetes (T1D) can be detected using biomarkers selectively discharged by dying beta cells into plasma.microRNA-375 (miR-375) ranks among the top biomarkers based on studies in animal models and human islet Stair Climbers transplantation.Our objective was to identify additional microRNAs that are co-released with m

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